Alexis \a-lexis\ as a boy's name (also used as girl's name Alexis), is pronounced a-LEX-iss. It is of Greek origin, and the meaning of Alexis is "defender, protector". Often used as a short form of Alexander, though it is from Alexius, the Latin spelling of the Greek Alexios. Saint Alexis (fifth century) was a popular saint of Edessa, venerated as a "man of God". Originally a boy's name, but now more commonly given to girls. Hockey player Akeksei Kovalev.
For more information, see also the related name Lexer.