Ephigenio \e-phige-nio, eph(i)-genio\ as a boy's name is a variant of Efigenio (Greek) and Eugene (Greek), and the meaning of Ephigenio is "well-born, noble".

The baby name Ephigenio sounds like Ephigenios, Ephigenius and Iphigenios. Other similar baby names are Efigenios, Eugenio and Ifigenio.