Eusebius \e(u)-se-bius\ as a boy's name is of Greek origin, and the meaning of Eusebius is "devout". Name of a few saints, the most famous of which was a fourth-century Italian bishop.

Eusebius has 11 variant forms: Esabio, Esavio, Esavius, Esebio, Eusabio, Eusaio, Eusebio, Eusebios, Eusavio, Eusevio and Eusevios.