Layne \la(y)-ne\ as a boy's name (also used as girl's name Layne), is a variant of Lane (Middle English), and the meaning of Layne is "path, roadway".

The baby name Layne sounds like Laine, Lanny, Lannie, Lewayne, Leone, Lynn, Lyn and Lonne. Other similar baby names are Bayne, Dayne, Gayne, Kayne, Mayne, Payne, Rayne, Wayne and Zayne.