Melesio \m(e)-le-sio\ as a boy's name is of Spanish and Greek origin, and the meaning of Melesio is "careful, attentive".

Melesio has 6 variant forms: Melacio, Melasio, Melecio, Melicio, Meliseo and Milesio.

Baby names that sound like Melesio are Miles and Myles.