Otis \o-tis\ as a boy's name is of Old German and Old English origin, and the meaning of Otis is "wealth; son of Otto". Mostly American use, probably due to composer Otis Redding. Actor Otis Skinner.

Otis has 4 variant forms: Oates, Otess, Ottis and Otys.

Baby names that sound like Otis are Odis, Addis, Athos, Ozzie, Waits, Watts and Yates.