Reuben \re(u)-ben\ as a boy's name is pronounced ROO-ben. It is of Hebrew origin, and the meaning of Reuben is "see, a son". From the original form Reuven. Commonly used since the 18th century. Biblical: Reuben was the firstborn of Jacob's 12 sons. Also a sandwich with corned beef, sauerkraut, and Swiss cheese. Reuven is a Spanish and Scandinavian form. Singer Ruben Blades.