Santana \s(a)-nta-na, san-tana\ as a boy's name (also used as girl's name Santana), is pronounced san-TAN-ah. It is of Spanish origin. A blend of Saint and Anna, after the fashion of Sinclair. Rock guitarist Carlos Santana has made the name familiar.

Santana has 1 variant form: Santanna.

Baby names that sound like Santana are Santino, Sandino and Swanton.