Ariadne \a-riad-ne, ari(a)-dne\ as a girl's name is pronounced ar-ee-AHD-nee. It is of Greek origin, and the meaning of Ariadne is "most holy". Mythology: Ariadne, daughter of Cretan king Minos, helped Theseus escape from the Cretan labyrinth. Saint Ariadne of Phrygia (second century) was a slave who became a martyr. Also the subject and title of a Richard Strauss play. Arianne and Arianna are the French and Italian versions now also used in the English-speaking world.