Emmanuelle \e-mma-nuelle, emman(uel)-le\ as a girl's name is of Hebrew origin, and the meaning of Emmanuelle is "God is with us". Feminine form of Emmanuel. Fashion designer Emmanuelle Khanh.

Emmanuelle has 6 variant forms: Emanuela, Emanuella, Emanuelle, Emmanuella, Emonualle and Emonualle.