Pearleen \pe(ar)-leen\ as a girl's name is a variant of Pearl (Latin), and the meaning of Pearleen is "pearl".
The baby name Pearleen sounds like Pearline, Perlline and Perline. Other similar baby names are Carleen, Karleen, Sharleen, Charleen, Darleen, Earleen, Harleen, Marleen, Pauleen, Pearlie and Pearle.