Prue \p-rue\ as a girl's name is a variant of Prudence (Latin), and the meaning of Prue is "caution, discretion".

The baby name Prue sounds like Pru, Bree and Brie. Other similar baby names are Drue, Arie, Cree, Dru, Page, Paule, Perle, Pris, Prudy, Prudie and Rue.