Samantha \s(a)-man-tha, sam(a)-ntha\ as a girl's name is pronounced sa-MAN-thah. It is of English origin. Feminine form of Samuel (Hebrew) "God heard". Also contains the Greek -antha which means "flower". Occasionally used in the 17th-19th centuries. Samantha became popular in the 1960s due to the TV show "Bewitched". Actress Samantha Eggar.