Saphron \s(a)-ph-ron\ as a girl's name (also used as boy's name Saphron), is a variant of Saffron and Sophronia (Greek), and the meaning of Saphron is "wise".

The baby name Saphron sounds like Sophrona and Saphronia. Other similar baby names are Simeron, Farron, Saffren, Saffran and Saphira.