Issie \i(s)-sie\ as a girl's name is a variant of Isabel (Hebrew), and the meaning of Issie is "God's promise".

The baby name Issie sounds like Essie, Assi, Izzie, Issy, Jessie and Josie. Other similar baby names are Cassie, Nessie, Lissie, Gussie, Bessie, Kasie, Casie, Kassie, Sissie, Cissie, Dasie, Lyssie, Ilse, Isme, Ilsaie, Ilsae, Ionie, Ibbie, Isis, Ivie, Kissie, Kessie, Lassie, Missie, Rosie, Susie, Tassie and Tessie.