Kathlene \k(a)-thle-ne, kath-lene\ as a girl's name is a variant of Catherine (Greek), Katherine (Greek) and Kathleen (Irish), and the meaning of Kathlene is "pure".

The baby name Kathlene sounds like Kathline, Cathlene, Kathlyne and Kathlena. Other similar baby names are Kathrene, Karlene, Kathryne, Kathrine, Kathleyn, Katheline, Cathlyne, Cathline, Kathlyn, Kathlinne, Kathlin, Kalene, Kateline, Katline, Katlyne, Kathyline, Kathlynn, Kathylyne, Kathleena, Kathaline, Kaylene, Kailene and Kaelene.